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Bernard-Soulier Syndrome Website

Model of GPIb alpha leucine-rich repeats
From: Whisstock JC, Shen Y, Lopez JA, Andrews RK, Berndt MC.
Molecular modeling of the seven tandem leucine-rich repeats within the ligand-binding region of platelet glycoprotein Ib alpha. Thromb Haemost 2002 Feb;87(2):329-33 [PubMed]

Side view of the model of human GPIb alpha leucine-rich repeats. Leucines of the repeat are in pink. The concave face, with the individual repeats numbered and the positions of mutations associated with Bernard-Soulier syndrome are shown as spheres


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